Pain Control In Chronic Non-Cancer Patients

Why would an article with such an esoteric title be of interest, of importance and relevancy to more than just Pain Management health care workers. Shouldn’t such an article be of more importance and interest in a Professional Journal than it would be to the educated general populous. What is behind the idea of publishing it on the Internet, situated so that many more than just medical minds would come across it by happenstance.

A large percentage of the general population is thought to either listen to, watch, or read any of the many ways the News Media bombards us with what their financial backers’ opinions would have us know. Therefore we must assume that this same population should, by now, understand how the median age of death, in our country as in others, has been prolonged. We attribute this increasing life expectancy, over the previous few centuries, by all of the many scientific advances, by the formation of and stabilization of standardized-religion, and by the many laws of behavior, in-acted to prevent man’s destruction of his/her fellow man/woman.

For these and other reasons, the percentage of the population living over the age of 65 increases with every passing decade and century. At this point I hope that you can begin to better understand the importance of pain control in chronic non-cancer patients. Since the percentage of the population over 65 is getting larger with each passing decade, it is becoming more common place to know or to know of an individual requiring pain control for a chronic non-cancerous problem.

Breakthrough pain in cancer patients is associated with poor outcomes, a greater incidence of hospitalization, more difficult to treat pain syndromes, and, of course, the inevitable patient dissatisfaction with therapy. None of the previous characteristics are found, in general, amongst the non-cancerous patients.

Breakthrough pain in non-cancerous patients is known to be prevalent, severe, and it shares several characteristics with cancer patients, such as that it is typically rapid in onset and frequently encountered. Studies have shown that nearly three quarters of patients with non-cancer pain have significant episodes of breakthrough pain.

For the general population, is not important what the actual treatments are for pain control in chronic non-cancerous patients. What is important for everyone to understand is that a growing part of our general population will be suffering with chronic non-cancerous pain. We need to start to modify and/or drop, when appropriate, our misconceptions of individuals (young and old) that complain of chronic pain that proves to be non-cancerous in origin. We must study how individuals on narcotic therapy do when attempting to continue with accepted normal daily functions. Such functions would include work, play, and care-giving. I feel that we will be surprised how much of a normal life these individuals can live if given the chance.

Generic Medications – The Truth Behind The Myths

These days the subject of generic medications troubles many “anxious about our health government minds “.Generic drugs are unsafe, not helpful as brand names for your diseases , they are made in unautorised facilities ect . Is this the truth or is it just an attempt to favour some american drug manufacturers and pharmacies.

Drug products sold in the United States are approved by the FDA whether they are brand name or generic. “Most people believe that if something costs more, it has to be better quality. In the case of generic drugs, this is not true,” says Gary Buehler, Director of FDA’s Office of Generic Drugs. “The standards for quality are the same for brand name and generic products.”

Health professionals and consumers can be assured that FDA approved generic drugs have met the same rigid standards as the innovator drug. To gain FDA approval, a generic drug must:

contain the same active ingredients as the innovator drug (inactive ingredients may vary)
be identical in strength, dosage form, and route of administration
have the same use indications
be bioequivalent
meet the same batch requirements for identity, strength, purity, and quality
be manufactured under the same strict standards of FDA’s good manufacturing practice regulations required for innovator products
So we can make the conclusion that: The Generic Drug is a drug which is bioequivalent to a brand name drug with respect to pharmacokinetic and pharmacodynamic properties. Generic medicines must contain the same active ingredient at the same strength as the “innovator” brand, be bioequivalent, and are required to meet the same pharmacopoeial requirements for the preparation. By extension, therefore, generics are identical in dose, strength, route of administration, safety, efficacy, and intended use.
Thus, in some cases, the “generic” product is actually the brand product but inside a different box.

The principal reason for the reduced cost of generic medicines is that these are manufacturered by smaller pharmaceutical companies which do not invest in research and development into new drugs. The significant research and development costs incurred by the large pharmaceutical companies in bringing a new drug to the market is often cited as the reason for the high cost of new agents – they wish to recover these costs before the patent expires.Other reason for high prices is that every year pharmaceutical companies spend billions to market their products.

When a pharmaceutical company first markets a drug, it is usually under a patent that only allows the pharmaceutical company that developed the drug to sell it. This allows the company to recoup the cost of developing that particular drug. It will frequently cost millions of dollars to develop and test a new drug before it is approved for use. After the patent on a drug expires, any pharmaceutical company can manufacture and sell that drug. Since the drug has already been tested and approved, the cost of simply manufacturing the drug will be a fraction of the original cost of testing and developing that particular drug.

So despite the strict standards imposed by the FDA for approval of generic drugs, and their enforcement of these standards, a number of misconceptions about generic drugs persist that we must disprove:

MYTH: Generics take longer to act in the body.
FACT: The firm seeking to sell a generic drug must show that its drug delivers the same amount of active ingredient in the same timeframe as the original product.

MYTH: Generics are not as potent as brand-name drugs.
FACT: FDA requires generics to have the same quality, strength, purity, and stability as brand-name drugs.

MYTH: Generics are not as safe as brand-name drugs.
FACT: FDA requires that all drugs be safe and effective and that their benefits outweigh their risks. Since generics use the same active ingredients and are shown to work the same way in the body, they have the same risk-benefit profile as their brand-name counterparts.

MYTH: Brand-name drugs are made in modern manufacturing facilities, and generics are often made in substandard facilities.
FACT: FDA won’t permit drugs to be made in substandard facilities. FDA conducts about 3,500 inspections a year in all firms to ensure standards are met. Generic firms have facilities comparable to those of brand-name firms. In fact, brand-name firms account for an estimated 50 percent of generic drug production. They frequently make copies of their own or other brand-name drugs but sell them without the brand name.

MYTH: Generic drugs are likely to cause more side effects.
FACT: There is no evidence of this. FDA monitors reports of adverse drug reactions and has found no difference in the rates between generic and brand-name drugs.

And finally what we can conclude is that the only “unsafe and unhealthy” thing about generics is the financial loss for the big pharmaceutical companies that want to protect their monopol on our health,despite the necessity of some low income households for effective medical care.

We believe that it takes knowledge & understanding to make wise decisions about the prescription meds that we take. In today’s society we are bombarded with huge amounts of confusing information about our health and the prescription drugs that are available. In an effort to clear some of this confusion we strive to provide you with as much information as possible concerning your health and prescription drugs.

So if you can afford to buy brand name medications, you can help yourself visiting our site, where we hope that you will find all the drug information that you seek to get rid of your diseases.

Treatment for High Blood Pressure

Blood pressure is the force of the blood pushing against the walls of the arteries. Each time the heart beats, it pumps blood through the arteries. Your blood pressure is at its highest when the heart beats, forcing blood into the arteries. This is called systolic pressure. When the heart is at rest, between beats, your blood pressure falls. This is the diastolic pressure. Blood pressure is always given as two numbers, the systolic and diastolic pressures. Both are important.

The systolic pressure is the first or top number, and the diastolic pressure is the second or bottom number (for example, 120/80). If your blood pressure is 120/80, you say that it is “120 over 80″.

It is important to take steps to keep your blood pressure under control. The treatment goal is to keep blood pressure below 140/90, or even lower for people with other conditions, such as diabetes and kidney disease.

Adopting healthy lifestyle habits is an essential and effective first step in both preventing and controlling high blood pressure. However, if lifestyle changes alone are not effective in keeping your pressure controlled, it may be necessary to take blood pressure medications.

The following types of medications are available to treat high blood pressure:

1. Diuretics: Diuretics are sometimes called water pills because they work in the kidney and flush excess water and sodium from the body, lowering blood pressure.

2. Beta-blockers: Beta-blockers reduce nerve impulses to the heart and blood vessels. This makes the heart beat slower and with less force. As a result of these drugs, the blood pressure drops and the heart works less hard.

3. ACE inhibitors: Angiotensin converting enzyme (ACE) inhibitors prevent the formation of a hormone called angiotensin II, which normally causes blood vessels to narrow. The ACE inhibitors cause the vessels to relax and blood pressure goes down.

4. Angiotensin antagonists: Angiotensin antagonists shield blood vessels from angiotensin II. As a result, the vessels become wider and blood pressure goes down.

5. Calcium channel blockers (CCBs): CCBs keep calcium from entering the muscle cells of the heart and blood vessels. This causes the blood vessels to relax and pressure goes down.

6. Alpha-blockers: Alpha-blockers reduce nerve impulses to blood vessels, which allows blood to pass more easily, causing the blood pressure to go down.

7. Alpha-beta-blockers: Alpha-beta-blockers work the same way as alpha-blockers but also slow the heartbeat, as beta-blockers do. As a result of using these drugs, less blood is pumped through the vessels and the blood pressure goes down.

8. Nervous system inhibitors: Nervous system inhibitors relax blood vessels by controlling nerve impulses, and this causes the blood vessels to become wider and the blood pressure to go down.

9. Vasodilators: Vasodilators directly open blood vessels by relaxing the muscles in the vessel walls, causing the blood pressure to go down.

To find out if you have high blood pressure consult your doctor and have a blood pressure test. The test is quick and painless.

To determine which life style changes and medications are appropriate, consult your doctor.